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i figure she could make things difficult for him

Bubble in brain.....even if he "aura" is there....she'll make one that seprates his brain with cells on one side and more cells on the other.....all this happenes if he doesnt speed blitz

He can use his x-ray vision to see her if she turns invisible.Superman wins.End of discussion.

superman is stronger, faster, smarter and his mind moves easily faster than hers...

Well seeing the general consensus is that Supes could take the entire fantastic 4 at the same time, there's pretty much no way for her to win this one. It's out of her character to try the brain bubble thing. Not to mention many have argued if its even possible. Either way Superman could take her at superspeed. And if she somehow managed to get a force field on him we all know that IW can't hold a shield to well if someone really powerful is beating on it. She either has to let go of the shield or pass out. Supes 10/10 IMO