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I got this idea from the Deadpool/Deathstroke thread.

Who wins in this fight to the death, or to the other is no longer able to compete? They both have their standard weaponry.

The setting is in NYC slums at midnight.

Blade is hyped up for his movies. Comic Blade would get owned so bad that he'd look worse than Deadpool.

That is a common misconception, but Blade is just like his movie verison now. He gained more powers after being bitten by Michael Morbeus. He would give Deadpool a fight.

Deadpool heals way way way way way faster.
Deadpool won't sie if decapitated, blade will.

Blade would work him for awhile,but deadpool will eventually get that skilled hit in that stuns blade enough to take conrol of the fight, then, deadpool decapitates him.

It will be a good fight, but Deadpool will get the win.

This is pretty evenly matched but I would say probably Deadpool........