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Lady Octopus
http://upload.wikimedia.org/wikipedia/en/f/ff/LadyOctopus.png
http://en.wikipedia.org/wiki/Lady_Octopus

vs

Madame Rogue
http://upload.wikimedia.org/wikipedia/en/5/58/Madame_Rouge.jpg
http://en.wikipedia.org/wiki/Madame_Rouge

noone?

Lady Octopus. Rogue has been shown to have been physically outmatched by some and mentally outmatched by those skilled. LO is very skilled and possibly much more physically dangerous. Anyone that can fight Scarlet Spider AND Spiderman at the exact same time is already incredibly powerful.