Well .. . let's just say I know someone who has. He had a year and a half relationship, and about a year into it she confessed to him that she had genital herpes, but since she used Valtrex religiously there was no way I would, I mean my friend would get it. As long as she did not have an outbreak he was okay. Since then my friend had an STD blood test and he totally came out negative for genital herpes.