I reckon Barney and Moe successfully double team Hulk leaving Nefaria to Homer. Nefaria gets the 1st punch in, only for Lisa Simpsom, sent to fetch her father home for dinner, walks in and distracts Nefaria with a philosophycal question, allowing Homer to smash him over the head with Barney's bar stool, ending the fight. Barney, however is not too pleased with his old friends actions as he is quite attached to that stool. The stage is set for another blockbuster of a punch up-but thats another story.
I think some of you are losing sight of the fact that this takes place in Moe's bar Spingfield, so i think some of the regulars such as Homer, Barney, Carl Carlson, Lenford (Lennie), the barfly with the cap and glasses, and the other drunk, will have a say in how this fight goes. What if Homer Lennie and Carl have an agreement with Fat Tony, of Springfields mafia-whereby they steal radioactive isotopes from the nuclear power plant, where the work which they sell to Tony in order for the mafia to build their own nuclear weapons. In the course of the fight the Hulk might be at as disadvantage as a result of Nefaria's greater range of powers. Coming into contack with the radioactive materila would give him a power booset which could turn the tide in his favour