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This is assuming that Itachi does not have a terminal illness.
Kakashi can use mangekyo sharingan (this is all in shippuden btw)
Pein has all six paths.

Here are their jutsus they can use:

Itachi:

Amaterasu
Clone Great Explosion
Crow Clone Technique
Demonic Illusion: Burning Paper Body
Demonic Illusion: Mirror Heaven and Earth Change
Demonic Illusion: Shackling Stakes
Ephemeral
Fire Release: Dragon Fire Technique
Fire Release: Great Fireball Technique
Fire Release: Phoenix Immortal Fire Technique
Scattering One Thousand Crows Technique
Shadow Clone Technique
Susanoo
Transcription Seal: Amaterasu
Tsukuyomi
Water Clone Technique
Water Release: Water Fang Bullet

Kakashi:

Jutsu/Weapon
Chidori
Demonic Illusion: Hell Viewing Technique
Earth Release: Earth Style Wall
Earth Release: Inner Decapitation Technique
Earth Release: Underground Projection Fish Technique
Eight Gates
Evil Sealing Method
Fire Release: Great Fireball Technique (Anime only)
Front Lotus (Anime only)
Hidden Mist Technique (Anime only)
Kamui
Lightning Blade
Lightning Hound
Lightning Release Shadow Clone
Multiple Shadow Clone Technique
One Thousand Years of Death
Rasengan
Shadow of the Dancing Leaf (Anime only)
Silent Homicide Technique
Summoning Technique (Dogs)
Summoning Technique: Earth Release: Tracking Fang Technique
Tornado of Water (Anime only)
Water Clone Technique
Water Release: Grand Waterfall Technique
Water Release: Water Dragon Projectile Technique
Water Release: Water Encampment Wall
Water Release: Water Shark Missile Technique
White Light Chakra Sabre

Pein:

Banshō Ten'in
Chakra Disruption Blades
Chibaku Tensei
Fierce Raining at Will
Five Seals Barrier
Flaming Arrow of Amazing Ability
Illusionary Dragon Nine Consuming Seals
King of Hell
Magic Lantern Body Technique
Mirrored Sudden Attacker
Sealing Technique Absorption Seal
Shapeshifting Technique
Shinra Tensei
Six Paths of Pain
Soul Removal (Unnamed)
Summoning Technique (Multiple)
Wind Release: Violent Wind Palm


who wins?

Pein just stomps this one.

Itachi and Kakashi own pain.

2 Genius with a high arsenal of jutsu against 6 bodies controlled by 1 person who just has an arsenal of jutsu.

Kakashi Kamuis 3 of the bodies. Itachi uses amaterasu on another 2. and susano'o the rest

Pein stomps hard.

Originally posted by Csdabest
Itachi and Kakashi own pain.

2 Genius with a high arsenal of jutsu against 6 bodies controlled by 1 person who just has an arsenal of jutsu.

Kakashi Kamuis 3 of the bodies. Itachi uses amaterasu on another 2. and susano'o the rest
Kakashi takes out three bodies when two easily owned him? WTF?

Originally posted by King Kandy
Kakashi takes out three bodies when two easily owned him? WTF?

Two didnt easily owned him. He was in control the whole fight. and disable one of the bodies before Chouza came into the picture. Pain had no idea where kakashi was and most likely kakashi could have cougth deva off guard if reinforcements didnt come in. So yes. And kakashi didnt use kamui on 3 of those bodies. Like he could have. Why because its takes to much chakra and there were mroe fighting to be done.

Given the situation they were in. If reinforcements didnt come. Deva would have most likely had been killed. And Asura destroyed throroughly.

Originally posted by Csdabest
Two didnt easily owned him. He was in control the whole fight. and disable one of the bodies before Chouza came into the picture. Pain had no idea where kakashi was and most likely kakashi could have cougth deva off guard if reinforcements didnt come in. So yes. And kakashi didnt use kamui on 3 of those bodies. Like he could have. Why because its takes to much chakra and there were mroe fighting to be done.

Given the situation they were in. If reinforcements didnt come. Deva would have most likely had been killed. And Asura destroyed throroughly. Keep thinking that.

Anyway, Pain for the win. One-shots both with Shinra Tensei.

Itachi solo..

Originally posted by Slaanesh
Itachi solo..
O RLY?!

Originally posted by ThunderGodEneru
Keep thinking that.

Anyway, Pain for the win. One-shots both with Shinra Tensei.

When has Shinra Tensei killed anyone? at best it broken Shikamaru leg.

http://www.onemanga.com/Naruto/422/15/
one body down and deva is paralyzed

http://www.onemanga.com/Naruto/422/17/
Kakashi was prepared for it and as you see his hand is filled with raikiri. He could have easily struck down pain while off guard. nothing would have stopped him. He even thanks them cuz now he can save chakra. Hell he could have easily kamuied Pain head off at that time.

So no. Kakashi didnt get owned. Chouji and Chouza screwed things up

If he'd Raikirid God Realm could have just repelled it.

5 second rule. Pain just used bansho tenin needing another 5 second recharge. That and he had no idea where kakashi was. So how is he going to repelle something he doesnt see coming?

Originally posted by Csdabest
5 second rule. Pain just used bansho tenin needing another 5 second recharge. That and he had no idea where kakashi was. So how is he going to repelle something he doesnt see coming?
It repels everything around him. Also Kakashi hadn't figured out 5-seconds yet.

Ah but you dont need to know it in order for you to take advantage. Pain would have been screwed.

Also pain has shown to do it in just 1 direction. And pain wouldnt know when to use Shinra tensei because he has no idea where kakashi is. Kakashi aready cought him off guard once when he tried to kill Iruka. There is nothing stomping him from doing the same. But instead oc catching a sword. Kakashi rams a raikiri through the back of his head.

Originally posted by King Kandy
O RLY?!
yeah..one look into Itachi eyes from any of the 6 body..Tsukuyomi will take affect and the fight is over..

Originally posted by Csdabest
Ah but you dont need to know it in order for you to take advantage. Pain would have been screwed.

Also pain has shown to do it in just 1 direction. And pain wouldnt know when to use Shinra tensei because he has no idea where kakashi is. Kakashi aready cought him off guard once when he tried to kill Iruka. There is nothing stomping him from doing the same. But instead oc catching a sword. Kakashi rams a raikiri through the back of his head.

One direction? http://www.onemanga.com/Naruto/442/13/

Originally posted by Kento
One direction? http://www.onemanga.com/Naruto/442/13/ Um. yeah i think we all know he can do it in multiple directions. i really dont see the point of this. >_>

Originally posted by Csdabest
Also pain has shown to do it in just 1 direction. Then what did you mean with this?

Originally posted by Csdabest
When has Shinra Tensei killed anyone? at best it broken Shikamaru leg.

http://www.onemanga.com/Naruto/422/15/
one body down and deva is paralyzed

http://www.onemanga.com/Naruto/422/17/
Kakashi was prepared for it and as you see his hand is filled with raikiri. He could have easily struck down pain while off guard. nothing would have stopped him. He even thanks them cuz now he can save chakra. Hell he could have easily kamuied Pain head off at that time.

So no. Kakashi didnt get owned. Chouji and Chouza screwed things up It shattered the bones of Gamabunta and the other two giant toads in one attack.

http://www.onemanga.com/Naruto/434/10/

Are you going to sit here and tell me Itachi and Kakashi are more durable than them?

And Deva Pain wasn't paralyzed, Kakashi could Rakiri Asura Pain all he wants, it would matter not when Shinra could then kill him.

Factual statement: Even with the help of others, Kakashi lost to two of Pain's bodies, one of the bodies was destroyed in a cheap-shot. And you think Kakashi can fight all of Pain's bodies at once? Idiotic.

Originally posted by ThunderGodEneru
It shattered the bones of Gamabunta and the other two giant toads in one attack.

http://www.onemanga.com/Naruto/434/10/

Are you going to sit here and tell me Itachi and Kakashi are more durable than them?

And Deva Pain wasn't paralyzed, Kakashi could Rakiri Asura Pain all he wants, it would matter not when Shinra could then kill him.

Factual statement: Even with the help of others, Kakashi lost to two of Pain's bodies, one of the bodies was destroyed in a cheap-shot. And you think Kakashi can fight all of Pain's bodies at once? Idiotic.

You must look at what they were slung into. They all hit something hard and crashed in mountains. Shinra tensei by itself does nothing but push people back. All those who didnt fly back hard into something got out with minimal damage. Kakashi was slung into a building and was in rubble and still was fine. Not only that but Kakashi knows Pain secret of his jutsu and what is capable of beating it. Wall climb. If he performs his chou shinra kakashi and itachi will most likely survive. And The main pain would be out for like 10 mins. And Pain has no defense against Susano'o or Kamui. Yet counters for Pain are availble.

Originally posted by Kento
Then what did you mean with this?

I was just adding to the fact that he can also direct it into one direction. I wasnt implying he can only do it in one direction. He mostly does it in one direction unless he is surrounded.

lmao at thinking this team wins or that kakashi (who pain wasnt even trying to kill initially,) had a goodchance of taking Godrealm on is own.

well..i think Itachi can take Pain by himself..he don't need Kakashi..

Originally posted by Slaanesh
well..i think Itachi can take Pain by himself..he don't need Kakashi..
You think wrong.

Originally posted by King Kandy
You think wrong.

how do u know i'm wrong??maybe u r wrong

I know you're wrong because Pein has displayed the abilities necessary to defeat Itachi and Itachi hasn't shown he can beat Pein.

what??he has Tsukuyomi which i believe can onshot Pain..one looked into the eyes and it's over..he has susano that makes him completely invulnerable..he has Amaterasu that can oneshot any off the 6 body..and he's fast..way faster than pain..

Originally posted by Slaanesh
what??he has Tsukuyomi which i believe can onshot Pain..one looked into the eyes and it's over..he has susano that makes him completely invulnerable..he has Amaterasu that can oneshot any off the 6 body..and he's fast..way faster than pain..
Tsukiyomi can take out one Pain body. Unless he hits the revival pain first, he it'll be back.

Susanoo can kill him if he uses it to long, so Pein can just stay out of range.

Ametarasu can be absorbed by the absorbing Pein or repelled by god realm.

Now, speaking of techniques, how could Itachi survive a Shinra or Chibaku?

Originally posted by King Kandy
Tsukiyomi can take out one Pain body. Unless he hits the revival pain first, he it'll be back.

Susanoo can kill him if he uses it to long, so Pein can just stay out of range.

Ametarasu can be absorbed by the absorbing Pein or repelled by god realm.

Now, speaking of techniques, how could Itachi survive a Shinra or Chibaku?

all their eyes are link with the real Pain..Pain sees through those 6 body..if one get caught with Tsukiyomi..i bet the real Pain will have the same effect..all u have to do is look into Itachi eyes and it's over..

what??when did he says that he can't use it for long..when we saw him using it..he was already dying

okie..maybe it won't work on those two..

with susano maybe..and he can move faster than Pain..Pain won't use Chibaku if Itachi is close to him..

That "all-eye" argument has never really been supported by anything. They all hear what the other bodies hear, but the toad-genjutsu only affected the three bodies that heard it. The Genjutsu seems isolated and if worst comes Nagato could just cut off and restart their chakra to escape like Kirabi did.

He can use it for a while but it drains his life to use so Pein can just fly higher than it's reach and Itachi will have to stop it... plus Chibaku could probably seal susanoo in stone if he needs to.

Since when is Itachi faster than Pein? Maybe he is but he has to deal with six bodies so he'd have to be like 6x Pein's speed to deal with them all.

Originally posted by King Kandy
That "all-eye" argument has never really been supported by anything. They all hear what the other bodies hear, but the toad-genjutsu only affected the three bodies that heard it. The Genjutsu seems isolated and if worst comes Nagato could just cut off and restart their chakra to escape like Kirabi did.

He can use it for a while but it drains his life to use so Pein can just fly higher than it's reach and Itachi will have to stop it... plus Chibaku could probably seal susanoo in stone if he needs to.

Since when is Itachi faster than Pein? Maybe he is but he has to deal with six bodies so he'd have to be like 6x Pein's speed to deal with them all.

the toad-genjustsu did effect nagato..that 6 body is nagato..it's just that that genjutsu kill those body..not nagato himself..dude..Tsukiyomi is not some stupid genjutsu u can escape with just cutting off chakra..Kirabi escape because he got the 8-tail beast inside him..Pain doesn't have that..

ah man..Pain can fly..i forgot that..okie..maybe he can seal susano..

Itachi is faster..he has better speed feat..much better that those 6 body..and he's a better fighter with more skill..

It didn't incapacitate Nagato because otherwise the other three bodies couldn't have come and revived the others. Only the three bodies that heard it were affected. There is absolutely zero evidence suggesting otherwise. And yes, cutting off your chakra can stop Tsukiyomi... that's how Kirabi escaped. The beast cut off his chakra. No different from what Nagato could do except it would be nagato instead of 8-tails doing it.

So yeah, none of Itachi's primary jutsus can take out Pein. On the other hand God realm's three jutsus can hurt Itachi.

He may be faster but Pein can fly so his hand-to-hand combat won't be getting Itachi anywhere... the six bodies could also just gang up on him.

Originally posted by King Kandy
It didn't incapacitate Nagato because otherwise the other three bodies couldn't have come and revived the others. Only the three bodies that heard it were affected. There is absolutely zero evidence suggesting otherwise. And yes, cutting off your chakra can stop Tsukiyomi... that's how Kirabi escaped. The beast cut off his chakra. No different from what Nagato could do except it would be nagato instead of 8-tails doing it.

So yeah, none of Itachi's primary jutsus can take out Pein. On the other hand God realm's three jutsus can hurt Itachi.

He may be faster but Pein can fly so his hand-to-hand combat won't be getting Itachi anywhere... the six bodies could also just gang up on him.

it did..they can't move..mean nagato can't move..those body are just puppet..it doesn't have a mind..they are all nagato..nagato can't move those body because he was affected by the genjutsu..no..kirabi escape because of 8-tail..he can't escape Tsukiyomi without 8-tail..Pain doesn't have anyone to help him..

Originally posted by Slaanesh
it did..they can't move..mean nagato can't move..those body are just puppet..it doesn't have a mind..they are all nagato..nagato can't move those body because he was affected by the genjutsu..no..kirabi escape because of 8-tail..he can't escape Tsukiyomi without 8-tail..Pain doesn't have anyone to help him..

This logic is just completely unsupported by anything. It even clashes with the way all genjutsus work. Itachi soloing pain is quite laughabke indeed.

Shinra tensei oneshots both kakashi and itachi easily. Matchover.

Originally posted by Csdabest
You must look at what they were slung into. They all hit something hard and crashed in mountains. Shinra tensei by itself does nothing but push people back. All those who didnt fly back hard into something got out with minimal damage. Kakashi was slung into a building and was in rubble and still was fine. Not only that but Kakashi knows Pain secret of his jutsu and what is capable of beating it. Wall climb. If he performs his chou shinra kakashi and itachi will most likely survive. And The main pain would be out for like 10 mins. And Pain has no defense against Susano'o or Kamui. Yet counters for Pain are availble.

Actually two of the frogs crashed into trees or simply the ground. It wasnt the landing thatdid it but rather the concussive force of shinra tensei itself. Its a wave of concussive force that repels evrything from pain. ITs not some form of wind that blows things away. Shinra hits with enough concussive force to turns buildings into rubble and even cause damage to the ground itself. If he uses an attack even remotely close to the one he used on Gamabunta and his crew then kakashi and itachi will both be dead. And there is nothing stopping him from doing so.

Originally posted by Naija boy
This logic is just completely unsupported by anything. It even clashes with the way all genjutsus work. Itachi soloing pain is quite laughabke indeed.

Shinra tensei oneshots both kakashi and itachi easily. Matchover.

genjutsu effect the mind or sense..those dead body doesn't even have a mind or any other sense..it's all nagato..don't tell me u actually think that genjutsu work on dead body

Tsukiyomi oneshots Pain easily. Matchover

Originally posted by Slaanesh
genjutsu effect the mind or sense..those dead body doesn't even have a mind or any other sense..it's all nagato..don't tell me u actually think that genjutsu work on dead body

Tsukiyomi oneshots Pain easily. Matchover

Retarded. Genjutsu works by manipulating the chakra in ur opponent nervous system by extending ur own into them. The bodies animated by nagato have fullly working senses hence the reason they were able to hear Jiraiyas genjutsu in the first place. It had to go diretly into their physical ears(we saw such n panel). Without nagato being present their is no way it could have worked. The same goes for tsukuyumi . Tsukuyumi can only work on the pain body its directed at. It will only succeed in weakening itachi and leving him open for attack. He would be oneshotted by shinra tensei before hand anyways.

Originally posted by Naija boy
Retarded. Genjutsu works by manipulating the chakra in ur opponent nervous system by extending ur own into them. The bodies animated by nagato have fullly working senses hence the reason they were able to hear Jiraiyas genjutsu in the first place. It had to go diretly into their physical ears(we saw such n panel). Without nagato being present their is no way it could have worked. The same goes for tsukuyumi . Tsukuyumi can only work on the pain body its directed at. It will only succeed in weakening itachi and leving him open for attack. He would be oneshotted by shinra tensei before hand anyways.

what??dead body doesn't have any sense..they never shown any..when they got hit..they don't show any kinda pain..cuz they don't feel any..they are dead..u got me..dead..genjutsu don't work on dead people..they have chakra that nagato give them..but what would genjutsu do to a body with chakra but no mind..nothing..that toad genjutsu..when u hear the sound..it paralyze u rite cuz i don't really remember..nagato heard that sound..so he must be paralyze..that's why those body can't move..u said that genjutsu work by manipulating chakra..nagato chakra is conected to those body..

Nagato COULD move though because the other bodies were perfectly functional when the toad genjutsu was used. Only the bodies that it targeted were affected. That's the fact of the situation and facts>opinions.

those body came after the genjutsu is finish..how do u know they were perfectly functional before that..u don't have any fact..neither do i

Originally posted by Slaanesh
those body came after the genjutsu is finish..how do u know they were perfectly functional before that..u don't have any fact..neither do i
So stop acting like you know these things when you just admitted you don't.

Originally posted by King Kandy
So stop acting like you know these things when you just admitted you don't.

u don't know about those thing too..and u seem to have no problem acting like u do..so why can't i do the same??

Originally posted by Slaanesh
u don't know about those thing too..and u seem to have no problem acting like u do..so why can't i do the same??
Because you were the one making the claim that Tsuki would transfer bodies. I said it wouldn't. You made the initial claim, you have to prove it.

Originally posted by King Kandy
Because you were the one making the claim that Tsuki would transfer bodies. I said it wouldn't. You made the initial claim, you have to prove it.

those dead body were affected by that toad-genjutsu..and jiraya said that the toad-genjutsu affect the mind, nerve and body all at once..those dead body doesn't have a mind and nerve..all they got is body..how the hell does that genjutsu effect them then..that's why i assume it actually affect nagato himself..but because he's not there..he didn't get impale with a sword..after it's all over..the other 3 body came..and Tsuki works on whoever looks into the eyes..nagato sees whatever those dead body sees..so..i assume it would affect him..nagato chakra is connected to those body too..

so tell me..why do u assume that it wouldn't work??

Originally posted by Slaanesh
what??dead body doesn't have any sense..they never shown any..when they got hit..they don't show any kinda pain..cuz they don't feel any..they are dead..u got me..dead..genjutsu don't work on dead people..they have chakra that nagato give them..but what would genjutsu do to a body with chakra but no mind..nothing..that toad genjutsu..when u hear the sound..it paralyze u rite cuz i don't really remember..nagato heard that sound..so he must be paralyze..that's why those body can't move..u said that genjutsu work by manipulating chakra..nagato chakra is conected to those body..

Sigh. Nagato wasnt shown in any way to be affected by Jiraiyas genjustsu. That is entirely baseless. The Pain bodies were physically fully functional bodies all that they lacked was their own psyche or consciousness. Hence their physical senses were operating. Even Jiaraiya said that the jutsu parlayzed the nerves in their body which means that said nerves must have been functioning before hand. The sound waves from jiraiyas genjutsu had to enter the physical ears of the pain bodies for it to work as shown here.
http://www.onemanga.com/Naruto/379/03/

IT obviously didnt enter nagatos physical ears since he wasnt even present at the battle so therefore there is absolutely nothin indicating that he was affected.

Originally posted by Slaanesh
those dead body were affected by that toad-genjutsu..and jiraya said that the toad-genjutsu affect the mind, nerve and body all at once..those dead body doesn't have a mind and nerve..all they got is body..how the hell does that genjutsu effect them then..that's why i assume it actually affect nagato himself..but because he's not there..he didn't get impale with a sword..after it's all over..the other 3 body came..and Tsuki works on whoever looks into the eyes..nagato sees whatever those dead body sees..so..i assume it would affect him..nagato chakra is connected to those body too..

so tell me..why do u assume that it wouldn't work??
You are basing your theory on absolutely nothing. There is not one shred of evidence Nagato was effected by the genjutsu. None. Please just cut it out.

a dead body with black rod piercing all over it that is fully functional like a normal one..yeah rite

that is just a form of chakra or sound that enter the ears..if it sound..nagato can hear it..mean it can affect him..if it's chakra..nagato chakra is connected to the body..means it can affect him..

okie guys..i'm getting board of this argument..so..lets just agree to disagree

now i dont really have proof for my next statement, just an assumption... that in mind ill speak.
Rinnegan has been declared the strongest of great eyes, so i believe tsukuyomi first off could be fought off from the rinnegan and secondly, if not, pain could disconnect his control from the affected body.

Amaterasu i believe could be warded away by a shinra tensei given that they both stem from their kekke genki and that rinnegan is stated to be stronger.

Susuno would be the main problem for pain in my opinion... Pain would be forced to run from itachi unless Nagato is allowed to use his own abilities... namely the summon that extracts the souls from anything it touches, perhaps chibaku tensei would successfully counter this as well considering it could crush itachis body against his own spirit weapons or bansho tenen could pull his weapons away from itachi

so pain wins imo

Edit: oh i consider kakashi a near nonfactor in this fight...

Also I see no reason why Shinra Tensei could not deflect susanoo like it did those Giant Frogs, it's omni-directional so it couldn't be shielded. And yeah, Chibaku could seal Itachi in Susanoo mode.

Originally posted by Naija boy
Pein stomps hard.

this guy destroys villages like nothing. Can bring his defeated paths back to life. semi-owned jariaya who itachi seemed very reluctant to face. I don't think even madara could handle him. seemed to be following orders since it was part of his destiny to end war.

Originally posted by Slaanesh
well..i think Itachi can take Pain by himself..he don't need Kakashi..

did he not tell kisame that even both of them could not defeat jaraiys him WITHOUT DYING?

Pain beat Jiraiya because he didn't know Pain technique..if Jiraiya knows it..he would have beaten Pain..i think Jiraiya can beat Pain , Itachi or Kisame one on one..

Originally posted by Slaanesh
Pain beat Jiraiya because he didn't know Pain technique..if Jiraiya knows it..he would have beaten Pain..i think Jiraiya can beat Pain , Itachi or Kisame one on one..
How the hell would Jiraiya be able to defeat Nagato when even stepping into his presence would cause Nagato to have control of Jiraiya's body? Nagato has the power of all six peins, if Jiraiya couldn't beat the peins then he cannot beat Nagato.

Pain 10/10

nagato stomps.

- iirc genjutsu doesn't work too well on him, and ninjutsu would get absorbed by fat pein.

- and speaking of fat pein, he's absorb amatarasu and quite possibly karui (spelling), animal path can summon him to block if he can't repel stuff with the gravity thing.

- his offense with only his gravity power is unavoidable

- and naraka path can reincarnate downed paths, most likely even deva path. that means he can almost never run out of troops.

- and most importantly, nobody knows about nagato's location or the fact that he even controls pein like puppets. the best the team can do is stalemate.

Even if they DID find Nagato's location I don't think either of them could resist his chakra taking over their bodies.

point on the itachi running from jiraiya... Kisame did comment after asking why it was necessary for itachi to run... itachi seemed to run for more of Kisame's sake much like him not waiting Kisame to fight kakashi

nah, itachi never wanted to cause a war with the leaf since it would impact sasuke whom he was taking care of from a distance. plus he has that pact with the 3rd.

he also knew that at his level, kisame would destroy sasuke since only itachi would show restraint towards him. he even wasted his remaining chackra drawing out orochimaru solely for removing him from sasuke.

Itachi killed Nagato who was a stronger version of all the Pain's combined with one attack. Itachi solos while shaking his head in disappointment as Kakashi shits his pants knowing he's next.

Itachi is a great strategist, he also knows how pains abilities work. The myteriousness of peins powers are his greatest strength but alo his weakness. Naruto was able to defeat him because he was informed of his powers and created strategies against them. We all know that both Itachi and kakashi are leagues smarter than naruto so the two of them could create a fool proof strategy to defeat Pain. Also itachi has abitites that are undodgeble by pains standards. Pein isnt fast enough to outrun amaterasu or susanno. Izanami is unavoidable. Susanoo is ridicously powerful and defensely worthy to defend against attatcks. This along with kakashis extremely large repetoire or jutsus including kamui. could prove more than a match for the 6 paths

Itachi's going to solo. Mobile Nagato vs Itachi and Kakashi would be a good fight though.