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This is Archenemy from the mini where it took on the combined Demon Lords.

1) Straight up fight one-on-one.
2) Amatsu-Mikaboshi gets all his slave gods to help him.

Now this is a good fight.

1) Who knows we'll have to see more of him in action.
2) They are of absolutely no help. Archenemy's single blast killed hundreds of thousands of death gods and demons.

From what we've seen so far, I'd say Archenemy

Archenemy.

So far only skyfather Herc is spooked by Mika. nightmare of course was spooked but he's dead. Hela as well...

...but all the Lords of the Splinter Realms were shook of Archenemy. Dormammu, Mephisto, Surtur, etc.

Archenemy is pretty much unstoppable in magic. It could only be defeated when the source of it's power was destroyed.