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Lets go back to the point during COIE where the Anti-Monitor was about to kill Superman and Supergirl entered the fray...

Lets pretend for a moment that Thanos entered the fray and attacked the Anti-Monitor instead of Supergirl...

How would Thanos perform against the Anti-Monitor at that point in time compared to Supergirl?

Interesting poll results...

I must say, in all fairness to Supergirl, she was a Pre-Crisis Kryptonian performing at her very best in this instance...

Anyone care to defend their vote?

Thanos gets killed in one attack.