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Dr. Octavius from Spiderman 2.

VS

Dr. Connors from Amazing Spiderman.

The fight takes place inside of Oscorp building from ASM.

Who wins and why? And who's a better scientist, Ock or Connors.

Ock's the better scientist. Ock's self-sustaining fusion core was more impressive than Connors regeneration formula, imo.

Fight, I'd likely give it to the lizard, that HF is above Wolverine's.

Nope, the HF isn't above Wolverine. And I see this fight as a tossup

Cooners need help from Parker or Parker's dads research to complete his experiment. Bank vault door or the steel frame that Ock crushed compare Lizard's arms and legs?