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When Thor battled the Stranger who put him on Ego. He learned he has some astral influence much like The Silver Surfer has for his life.
Knowing that the heros learn from their own lives do you think that Thor is now prepared for the final battle against Mephisto?

Mephisto turns Thor into one of his pet Ghost Riders, like he did to Jane-Thor, Doctor Strange and countless others during Doctor Strange: Damnation event.

If Mephisto is fighting Thor for his soul then Thor wins. Mephisto has tried repeatedly to corrupt Thor and failed.

If Mephisto doesn't care about Thor's soul and just wants him dead, Mephisto wins. In or out of his realm.

I'm going with Thor on this one.