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Originally posted by cdtm
The Destroyer armor was designed to fight Celestials, and had power from multiple Skyfathers. It's probably more powerful than any single Skyfather, and Thanos didn't do so well when he fought a Skyfather (Unless you count taking an extended beating and being alive as "doing well")

Further, there's really nothing Thanos could do to harm the Destroyer armor. He's lose in the end, if not immediately..

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Originally posted by Digi
It was designed to fight the Celestials. That doesn't mean it's that powerful. It did remarkably poorly when put into action, and was utterly trashed by them. Thor has dented it as well.

Tbh, it fluctuates depending on the strength of who is inhabiting it (and it needs someone inhabiting it, or it's just lifeless armor). So this fight could go either way.