Animal claws are made of keratin, not bone. In Creed's case, that must be some super-durable keratin.
Claremont did state in a non-canon comic they are made of bone, though. Makes no sense, but it's comics. I guess the best it's to call them "organic", that way we won't be making any mistakes.
Mindcontrol is a really cheap win, but yeah, he's shown he is capable of it in one of his minis.
In an actual fight, BC Wolverine managed to stalemate him, despite getting one set of his claws eaten...
Cletus and easily. Cletus would love this fight. Two guys who he can ragdoll and easily subdue in his symbiote and torture at will, whondont have the strength between them to mount any effective counterattack, while he is chopping them to pieces with flechettes faster than bullets. And they keep healing. Hed probably haave another baby.