The Ordo Hereticus (Warhammer 40000) vs Hogwarts & Twilight Vampires
The Ordo Hereticus branch of the Inquisition lays siege to Hogwarts.
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Hogwarts is fully supported by staff and students along with Voldemort and his Death Eaters, as well as having support from the Volturi and Cullens from Twilight. (Book version I guess, though can change if movies offer a better challenge)
The Ordo Hereticus force is led by a psychic Lord Inquisitor in power armor and wielding a force sword and inferno pistol, and carrying a rosarius accompanied by a retinue of psykers, pentinents, and combat servitors.
His force consists of a Commandery of 200 Battle Sisters, consisting of alongside normal troops Celestians, Seraphim, and Retributors, led by a Canoness (Their typical armory linked here), driven into battle by Rhinos and Immolators, along with half a dozen Penitent Engines
Along with them are a company of Storm Troopers, sent into battle in Chimeras.
Well, I'm pretty confident that the Twilight vampires are fast and strong enough to deal with the stormtroopers, along with their powers. Don't know if they're strong enough to deal with power armor though. Wizards might be able do something, not sure, been awhile since I read or watched Harry Potter.
Probably won't be able to really do anything to the transports and tanks, though Pentinent Engines are that open-topped nonsense.
The Inquisitor and Eversor are just lol though. Both are fast and strong enough to deal with vamps.