Big Blue can take that massive level of punishment, but what happens when he starts taking an endless amount of Star level punches? Asura's physical strength has a greater gap that between Supes and characters like Darkseid or Doomsday, so I would assume he could be downed after a lengthy fight from someone like Asura.
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"Gonna need more chloroform..."
"If you look down on us, judge us, condemn us... then you shall fear us!"
Because we have Superman treating a fraction of a nanosecond as if it were several minutes to him.
Even much higher end, we have him matching Barry Allen's perception speed in the Superman: Grounded series, and that was in the same book that Barry bragged about being able to see events at Attoseconds.
Both feats, put him massively, massively faster than light.
You have to use Superman's most absolute highest feats. On his lower end or averages, I don't think he can even stand up to Six Armed Asura, who did punch Wizen to death. Say what you will, but he was at least a time or two larger than Earth and Asura killed him with punches.