Here's how it works, a poster will give a what if(DC or Marvel) story that they would like to see, than the next poster will comment on it then give the title of a story they would like to see. I'll start....
What if Aunt May was the one bitten by a radioactive spider?
What if Reed Richards an Dr Doom never really did that well in school?
What if Xavier never got crippled by an Alien in Tibet but got in a car and accidentally ran over Magneto's back?
What if Superboy prime wasn't written as a walking plot device/emo?
What if Wolverine comics were actually quite well written?
What if What if stories became cannon?
What if the phoenix force actually turned out to be a perfectly mundane, benevolent alien entity that just wanted to sit down and have a chat?
What if Batman wasn't cool?
What if Daredevil was just joking all along and could tell how many fingers you were holding up?
Captain America would be dead. Wolverine would have been reincarnated, and extremely wise. Ironman would have supertech out the wazoo. Hulk would be the strongest one ever, and be not dissimilair from Planet Hulk.