collossus can do some pretty mean physical damage, but with venom's insanely fast healing factor, and collossus not being able to manipulate the symbiote's weaknesses (fire and sonics) then this one goes to venom.
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This is very similar to the fights:
Venom vs. Hulk
Venom vs. Juggernaut
in that, Venom is much quicker and able to get off many more hits than his opponent (though not shown in the Juggs match up)...but the fact of the matter is....Venom's blows are not all that effective.
Collossus wins...because eventually he gets his hands on Venom...and that's all she wrote.
I agree once colossus get his hands on venom this party is over. Hell snap his neck like he did to riptide. Even with a healing factor he wont survive that.
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Battle remove is Venom's only hope. It's going to take hours or more if Venom can keep a good distance. Venom's Class 11 so he can easy web Colossus and throw him about. It won't do much but he can piss Colossus off enough to quit after realizing it be a waste of time to continue.
piss off?, id say annoy at best, and colossus inst slow, he does have enhanced reflexes, not as fast as venom but mutch faster than normal people, colossus wouldnt just stand there, he could catch a web, pull venom in and beat him like a ragdoll
i'm guessing all of you are forgetting that venom's "skin" or whatever is toxic, and seeing as collossus (while in reg. continuity, NOT ultimate) still breathes oxygen and has "gooey" insides, he can be killed through the fumes...