And maybe if we cannot answer that question independently of us... it could mean that the universe depend on us in someway.
To say that something exist we must be able to observe it in someway, right ? This universe that we speak about consists of all our observations, and sensations from it. If we were not here this same universe of observations, and sensations would not exist, so it will change a lot since it will not exist anymore. If you are thinking about a universe which is not this universe of observations, and sensations, then you are thinking about a metaphysical concept(like God), and maybe this metaphysical universe could not change with our absence, but a universe like this is not real in my opinion.