This fight would be between Deadpool and Deathstroke. Since they both carry guns (to my knowledge at least in reference to DS), it's really whoever gets the first shots off. Both Wolverine and Sabretooth go down to bullets, and then it just depends on who shoots the other one first between DP and DS.
And even without his healing factor, Deadpool can't die.
Sure he can shoot, it doesn't mean he'll get shot though.
Deadpool more then likely won't take out Deathstroke before he is downed, DS is a team wrecker with typical gear these street guys are gum under his boots.
Does Deadpool retain his super strength and physical abilities in this match? Either way, Deathstroke probably will still win this since his abilities are enhanced to a fair degree.
Slade wins this. Wolverine, iirc, is poisoned by the very presence of the adamantium in his body. His hf combats the poison. Without the hf, the poison will kill him. Fast. Not to mention, his age will catch up to him.
Wolverine's healing factor was okay even with the Adamantium poisoning. Without the poisoning, ie bone claw/current... he's horrifying good. Wolverine dies without his HF, just from the poisoning, he'd last all of 10 minutes. Can you imagine having 20 lbs of metal connected to the spinal column of a regular human body? And if he's dumb enough to unsheath the claws, he bleeds out. Which if he slips to berserker rage, he'll probably do.
Deadpool vs. Sabretooth vs. Deathstroke? Both kill off the big guy pretty easily and go mano a mano. (Sabretooth is strong, but slow, he'd make the obvious first target for their guns) Shooting off Deathstroke is a quicker opponent, more likely to dodge the attacks than Deadpool. I'd say Deathstroke in the end takes it just barely. After he puts a cap in Deadpools head. WHAMMO!
__________________ Quotes from Hia8:
"I claimed that the science is sometimes faulty."
"You don't understand. This is fiction. That means none of this stuff really happened."
"There is no writer to purposely ignore a character's natural ability just because it suits the story."
"in some cases because the writer knows that Character A will dominate Character B easily and refuses to allow this to happen for the sake of the story."