Gender: Male Location: In Luna's mane, chasing STAAARS!
In Bioshock 1, Splicers were scared of Big Daddies but in Bioshock 2, it looks like you're fighting a swarm of them. I think they got over their phobia.
Also, I have never seen a Splicer in Bioshock afraid of a Big Daddy, they almost always try to kill them.
EDIT: Actually who is to say almost all the ADAM is gone? I mean, Jack only explored a small portion of Rapture, and there are many more Little Sisters and as long as there are corpses, they can harvest ADAM.
Gender: Male Location: In Luna's mane, chasing STAAARS!
Well I guess it's rare to see a Splicer being afraid of a Big Daddy but don't you remember what happened in the first level? Jack was unconcious and there were two Splicers that were about to take his ADAM but they heard a Big Daddy coming and bolted.
One time I saw a Splicer across this room I was in and a Big Daddy was between us. After it left, the Splicer went after me. No joke. Eversince that happened I realized these guys must be really scared of Big Daddies.
So the discussion is that a splicer chased after the player once the Big Daddy was gone.
And that equals being scared?
Well, I do remember being attacked by splicers when a Big Daddy was in the room, also, the game is programmed so splicers do not attack Big Daddies unless its a scripted event.
And, at the start of the game, you see a Splicer run away when a Big Daddy comes.
So yes, splicers are generally scared off Big Daddies.
I managed to get two big daddy's to fight each other once, I got one with a swarm further on in a level, died then got one near the vita chamber, then the one I got earlier came after me and then I jumped out the way and hit the other big daddy and then once one of the big daddy's had won I just killed that one then saved both little sisters Good times
Gender: Male Location: In Luna's mane, chasing STAAARS!
Turns out you can actually scare off Splicers in Bioshock 2. In the OXM, 2K said that when you kill a group of splicers there may be one left and that last Splicer will run away.