Well, toward the end of their run in Action Comics, the duo were portrayed as being demi-god like entities which wound up beating some kind of artificial Kryptonian Rao construct or something or another, iirc. They would have to tap into their respective personas, imo, as they would probably get beaten decisively if they stuck with their standard Kryptonian powersets.
yeah, that construct was taking on various members of the JLA/JSA combined. Chris Kent did something to take him down, with Flamebird. Chris would be enough, IMO.