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Deadpool, The Dark Knight Joker and Sam Witwicky get locked in a small room together. There is also a self-triggerable guillotine in the room. Who snaps and beheads themselves first, and who is crazy/annoying enough to drive the others to that point? They are not allowed to physically harm each other.

Deadpool. Because he knows he will probably grow another head. maybe?

Sam will drive the others insane.