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I like the Samehada that Kisame from Naruto wields, and like Kenpchi Zaraki of Bleach's Zanpakuto, can't think of the most powerful right now.

An orbital frame.

I'd love to say Ichigo's bankai, but the swastika on the guard kind of messes it up IMO

hmmm, thats a hard one.

tessaiga from inuyasha is up there. so are sesshomaru's swords.
kusanagi from naruto. samehada too.
the large sword{forgot name} form tenjou tenge that belonged to shin and now aya.
the ice sword from flame of recca.
the gun that summons monsters from the final fantasy chronicles anime.
aizen/ichigo's zanpakuto/byakuya/hitsugaya's zanpakuto
the anti akuma weapon from d gray man
many of cross's and devils's weapons{boomerang} from satan 666
the multi typed scythe form flame of recca
X's buster variations from megaman
the compass and staff from one piece
dante's swords/rebellion/sparda/yamato plus his gauntletts and guns form devil may cry

I also like the Banryu wielded by Bankotsu from Inuyasha.

My favorite weapon is Allen Walker's arm (especially in its Crown Clown form ):

http://upload.wikimedia.org/wikipedia/en/8/8b/Omega_Allen.png http://upload.wikimedia.org/wikipedia/en/c/ce/Allen_stages.JPG

Caster Guns are pretty tight...

Buster Machine number 3

well as far as favorites go

it's a tie between Killy's GBE and Gene's caster.

Vash the Stampedes reveolver, or Nick Wolfwood's big ass cross machine gun

Bui's axe, or....the Blade Liger.

The weapons used in Beet buster are quite strong, can't remember the names. I'd say Tessaiga from Inuyasha.

The simple kunai ftw.

battousai's sword=major pwnage
kenshin rocks

1.Clouds sowrds in AC
2.Squalls Gunblade
3. Keyblades
3.Train Heartnet gun from Hades
4.Voltron sowrd

I cant think of any more those are just ones i could think of.

Cross Marian's Gun:
http://img515.imageshack.us/img515/753/crossmariandt1.jpg


Allen Walkers Crown Clown Suit:
http://img153.imageshack.us/img153/5682/largeanimepaperscansdgraa6.jpg

Originally posted by superkronick92
Vash the Stampedes reveolver, or Nick Wolfwood's big ass cross machine gun

those are pretty cool

but i got to say

Ichigos sword from Bleach when its in Bankai