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ok the spidermen are

Spiderman reg
iron Spiderman
Metal suit spiderman
scarlett Spider
Spiderman 2099

v.s

six villains chosen random

Omega red
Red Guardian 3
Dr. Octopus
Mole man
Lady Deathstrike
Green Goblin

since when was omega red part of the sinister six?

most of these have never been part of the 6 but i'm callin them sinister 6 cause there is 6 and they are fscing 6 different spidermen

I'm going with the 6. Hell, the Spidermen would have enough trouble with Omega Red by himself much less the whole group.