In Final Fantasy VII: Advent Children, two years after the events of Final Fantasy VII, Cloud has been affected by a disease known as "Geostigma", which is an effect caused by a natural eliminary reaction to the inherent unnatural Jenova cells. This is why Cloud's left arm is cloaked in Final Fantasy VII: Advent Children; to hide the disfiguration. Children affected with Geostigma have been taken captive by a trio of men: Kadaj, Loz, and Yazoo, who consider anyone with Geostigma or Jenova cells to be their "siblings". They plan to manipulate the children's infection of Jenova cells to lead them to Jenova's remains, allowing them to take part in a new Reunion of Jenova's cells and Sephiroth's divided Spirit Energy, of which they are the physical manifestations. This places the burden of saving the children upon Cloud. As Tifa states early in the film, Cloud must once and for all find that incredible strength he found during the final battle of Final Fantasy VII to save the future. This conflict is the basic plot element in the film, as Cloud comes to various conclusions as well as reaffirmations from his friends. Finally coming to terms with his self-imposed guilt, Cloud gives it his all in the end to show the villainous trio his true power, but not without some help from a departed old friend and his surviving comrades.
Cloud is featured with his new motorbike called "Fenrir" which features a sword rack built into the sides of the motorbike. He is also seen performing the Limit Break "Climhazzard" on Bahamut, limit break "Blade Beam" against the attack from Loz, limit break "Braver" on Bahamut, "Cross Slash" against Sephiroth and "Finishing Touch" during the battle against Kadaj throughout the movie (he uses all of his limits except for two: Meteorain, and the original version of Omnislash). Cloud has a very unique new weapon in Advent Children replacing the Buster Sword; the First Tsurugi (or "First Sword"
, which is in fact a weapon with the ability to separate and reassemble into smaller swords. Cloud is shown to be extremely powerful and skilled when he finally gives it his all, as Kadaj can barely even touch him in combat. This is a throwback to the finale of Final Fantasy VII, where Cloud seems to become a powerful SOLDIER on par with even Sephiroth after he comes to terms with himself. However, before the struggle can end, Cloud is in for one last big surprise at the climax of the film.