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Who wins? Personally I think it'll be Spidey 2099.

black panther is the superior fighter in here. BP claws would probably be a problem, but spiderman has super strenght, more speed and resistance, and can use his web to keep panther in the ground, i give him the victory.

but since BP is more experienced he could win some fights. and if he brings weapons to this fight spiderman could be screwed, altough miguel is not a dumbass either.

Black panther can beat any version of spiderman.

No, he can't. In fact, he's never gotten a solid win over Spider-man. He can't even get a solid win over Captain America.

Spidey 2099 wins.

Spidey is faster, stronger and more agile, his UMF (Unstable Molecule Fabric) suit will mean PB's claws can't cut through it, but PB's vibranium suit is vulnerable to sharp objects ... and it has even been torn by broken glass, so SM 2099's claws should be able to tear it apart.