Kain: Kain's very mobile, and can kill many of the heroes attacking the castle if he catches them alone, or in a small enough group. Sadly, he will not find this easy. His ability to gain lesser forms of his enemies abilities through blood, and TK will make him a slowly building threat, as he takes out enemies one at a time. His small time aura may also give hi ma chance to react to some ranged attacks that would otherwise be his undoing. He will struggle very hard against enemies with magic resistance, and Magebane will neuter him entirely. As such, Kain will spend a lot of time teleporting around the battle field, avoiding these characters. However, he is still very useful, as he can kill the majority of the enemies, should he manage to avoid the wrong ones, and the more dangerous ones are killed for him.
Priority: Medium-high. While very dangerous, he's entirely countered by certain heroes, and won't truly shine until they're eliminated.
Counters:
Chronos: With no blood to speak of, and time powers at his desposal, could badly wound and weaken Kain, and temporarily freezing him in time with a strike will let Valkyrie land a light javelin, or Accursed to immolate him. On his own, he would be unlikely to take Kain down, but with the right help at the right time, Chronos will be Kain's undoing. He can teleport after Kain, as well, making Kain's life hard. Fortunately, he may be vulnerable to the reaver, as he apparently has a soul.
Defiler: She can silence Kain, preventing him from using spells temporarily, including teleport. With no teleport, Kain becomes absolute bait for;
Magebane: Kain's ultimate counter, Magebane may even be able to take Kain on by himself, it seems he was designed to do so. With immunity to magic, a teleport, and the ability to drain magic from his enemies, he will quickly drain Kain's power, and possibly kill him. Kain may still best him in melee combat, however. But whenis Kain going to be fighting Magebane alone? Even if Kain teleports, Magebane has this power also. Luckily, Kain is not alone either, and any of his comrades, except Snake, could easily deal with Magebane. Chief especially with his plasma weapons.
Andromeda: Oh, Andromeda, brutally efficient for trappign an enemy that's a little too good at escaping. She can swap places with Kain at any time, putting him right where they want him. Probably between some combination of any of the people on this list. Unfortunately for her, he may just be standing next to someone she doesn't much want to be close to. But in terms of numbers, one sacrifice for the New earthers is a large win.
Glacius: Can freeze Kain's mist form, or Kain's vampire form, holding him still for the others.
Swift Blade: Able to temporarily become immune to magic, and attack much faster than Kain can react to, he's like a miniate Magebane with no teleport or mana drain.
Thunder Bringer: Can strike Kain with lightning, evaporating his mist or stunning him. This also illuminates Kain's location to all allies. Fortunately, he's frail in melee, and has a soul to be stolen, and this seems unlikely to mortally wound Kain.
PollyWog Priest: A brutal one. PollyWog priest can cast magical bindings which restraing a foe in place and prevent the use of any magic. This would be much harder on Sephiroth, who relies on his speed to avoid damage, but is still bad for Kain. No teleporting out means he has to hold still while bad things happen to him. Fortunately, I think a single bullet, arrow, plasma shot, or swording will be enough to kill Pollywog Priest before he achieves this end. It all depends who among the New Earther's dies first. This counters list will also help as a way of determining target priority among the New Earthers.
Pebbles: No blood, too durable to have his soul poked with the reaver, too heavy to TK, and can increase in size. Someone Kain will simply have to avoid.
Dark Lady: Able to move very quickly to Kain, and stop him from using magic with a strike, Dark Lady is akin to Magebane in her annoyingness. She can also make communication difficult for KMC's most wanted. Kain should avoid her as oft as possible, perhaps bloodshowering her at range, if he gets the chance. Shame he can't do this to more than one target at a time.
Accursed: The accursed can immolate Kain, erect shields for his allies, and can cause Kain great harm. Howeve,r this works both ways, as Kain obtained Pyrokenesis in Blood Omen 2.
Valkyrie: Light javelins. This is her main asset against Kain, however, it only really comes into play if she has support to nail him down.
Magmus: He can ride and hurl freakin' lava. 'Nuff said. That's a dead Kain if he gets close, end of.
Kain can counter: Many characters. Any softie with a soul that strays a little too far, and most which have blood to give. His pyrokenesis and time aura will be generally advantageous and his mobility will allow him to mostly evade his counters while the better equipped characters handle them. He could be the bane of weaker support heroes.
Hellbringer: Remember PollyWog Priest's lame binding ability? This guy has it too, and more, he can boil Kain's insides.
Sephiroth: Sephiroth's very fast, can can probably cut throguh the armour of his enemies with relative ease. He also has powerful TK, and good reflexes. All in all, he's a scarey premis for his enemies here. If left alone for too long, he can cause too many casualties for this to be allowed. Sephiroth should probably be killed first simply because of his speed, even if his over-all threat isn't the highest on his team. His TK is powerful enogh to affect multiple foes simultaneously, and his sword can cut through steel.
Priority:High.
Counters:
Andromeda: Andromeda again, has the power to essentially stick Sephiroth right where New Earth wants her, though she'll probably die as a result, she'll be doing her side a great favour in the process.
Glacius: Can freeze him with an AoE attack, though it will be much easier if someoen else traps him first, such as Pollywog Priest.
PollyWog Priest: Remember earlier when I said how bad this was for Kain? Worse for Sephiroth. Instantly binding him, Sephiroth's going to eat a lot of concentrated fire, and it eliminates his prime advantage. Speed.
Magmus: Melts Sephiroth the second he's held immobile or slowed down enough for it to happen.
Hellbringer: Like a Pollywog Priest on steroids.
Master Chief: He has access to futuristic weapons and armour, and as such, is an incredible physical threat. He's fast, durable, strong, and has guns. Unfortunately for Chief, he has no magic resistance whatsoever, and will find himself getting raped by characters with powerful spells. He's like an antithesis to Kain, and the two should work together to eliminate one another's counters.
Defiler: Remember how I said MC has no resistance to magic? Well, here's where it gets bad... She has a ranged magical attack which is incorporeal and goes through multiple enemies. Makes Chief's impressive armour seem less so. She can also send spirits to attack him. Useless armour is useless. Luckily, he can shoot back.
Glacius: Can freeze Chief solid, good luck dodging Defiler's attacks that way. Sad state. Again, howeve,r bullets hurt.
Keeper of the forest: Can restrain Chief's ground based self with roots and the like, though he's vulnerable to weapons fire.
Hellbringer: Can bind and boil. Chief's lack of magic ability or resistance really hurts here. Once boil and he's done. Thankfully, bullets are still useful here.
Magmus: Melts Chief is he gets bound or snared.