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http://en.wikipedia.org/wiki/Great_Old_One

Like all at once or just one? Galactus could beat one of them but all together they could probably take him down.

all at once including the elder gods(read link)
galactus is at 88%

Its difficult to gauge their power but I'd say the GOOs were individually at least Skyfather level and probably stronger.
Galactus loses.

Issues they appeared in?

Originally posted by Prep-Man
Issues they appeared in?
They're not comic characters. Ever heard of Cthulhu? He's one of them but there's like twenty or thirty that have appeared or been mentioned in books, only about ten of them were Lovecraft's though.

Originally posted by Colossus-Big C
all at once including the elder gods(read link)
galactus is at 88%

How come hes not at 65.55% power?

Originally posted by The Nuul
How come hes not at 65.55% power?
Or 39.675% power? At 39.675% power he gets a super-awesome jetpack and starts glowing red.

Methinks Chthulhu solos.

chthulu is the monster marvel got the characters Chthon and Shuma-gorath from after buying them, so he should be there levels comibined.

HERALD...MY RAGE!

Galactus brings the pain.... and the noise.