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Loki is inside destroyer in scenario 1
GL hal is inside in scenario 2

CIS PIS off
bfr off

amazo has core jla powers (wonder woman superman flash etc)
despero is at power level when he was litterally banging heads together (superman an hal) lol
amazo cannot copy powers

Thanos intervenes in both scenarios IF amazo or despero are killed an takes one of their places

destroyer is 8ft tall

You just removed Amazo's best chance of winning.