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Who wins?

Sersi.

Loki

I have to go with Loki on this one. I think that Sersi would do well for a period of time, but Loki would eventually get around her defenses with magic. I could be convinced otherwise though. I just think that Sersi would only be able to hold a defensive stance in this particular match, while Loki would be able to defend, while also going on the offensive. Again, I could be swayed to see this another way.