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Wesker from RE5.

VS

Alexia from Code Veronica and DSC.

Round 1: Base Wesker vs Alexia's first form.

Round 2: Uroboros Wesker vs Alexia's 2nd and 3rd transformation.

They fights on the Hall where Wesker fought Alexia for the first time.

Can Wesker win this time or Alexia still wrecks him?

Well we already know Wesker isn't a match for Alexia in base form, not sure how much Uroboros Wesker is going to help, he became stronger and more durable so I guess he could probably tank her attacks

I forgot how durable Alexia is, I just remember having to use a special weapon to kill her at the end of Code Veronica, although I played that game over a decade ago so my memory is fuzzy