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http://pre00.deviantart.net/eb54/th/pre/i/2011/073/c/3/isaac_clarke_by_ninjatic-d3bni8m.jpg

vs

http://static2.comicvine.com/uploads/original/11127/111279980/5348613-7511477942-27122.jpg

Both have Standard gear
Win via Death or KO
Battle in a Infected Spaceship with a lot of Infecteds

Who takes it?

What standard for Shepard?

Anything outside of his Commando set and I think he wrecks.

Originally posted by socool8520
What standard for Shepard?

Anything outside of his Commando set and I think he wrecks.
M-8 Avenger, M-92 Mantis, M3 Predator, Omni Tool and 3 Grenades

No Biotics/Engineer tech? If not, it's probably closer.

I still think Shepard wins most of the time. He was military trained, and wasn't Isaac just a miner to begin with?

Tough fight. I'll give it to shepard either mid range or at a distance. I believe biotics is greater than issac's ability to slow you down because the biotics allow for quick finishes of enhance ammo. From a distance abilities like throw just travel farther than Isaac's slow, so he's out gunned.