Deadpool is T'Challa's equal or superior in most regards. Physically, Deadpool is superhuman in every way that T'Challa is enhanced. The one thing that comes to mind that Black Panther DOES have over Wade is T'Challas insane senses. But that's all. (And the whole Vibranium suit/antimetal claws/kimoyo card/etc.)
Some would argue skill, as well, but that is only arguable - Deadpool has shown himself to be a fine combatant on Black Panther's level - once the two of them matched each other blow for blow, and even discussed technique while doing so. It really felt as if the writer was trying to imply an equality.
Gender: Male Location: On a rock, floating through space..
Two of my all-time favourite characters - but I think Deadpool has a slight edge, despite BP's technology. Deadpool also has a pretty impressive healing factor, as far as I recall...
Are we all forgetting BP's tech and suit. Deadpool would only be able to hurt BP with physical H2H in which they are equal. While Bp can use everything at his deposal to hurt Wade.
Plus, BP gets prep. When he gets prep he is next to impossible to beat.
T'Challa takes it. I think that even without prep he could take it. Both are resourceful, but TChalla is smarter. Skill, capability wise, its dead even to me, but TChalla figures things out.
With prep... this isnt even fair. 15 minutes is enough time for TChalla to call in some anti-Deadpool machine. The other 15 would be time for TChalla to pick up a couple super power babes !
BlackPanther deals with guns all the time.