I see it as a group battle of one-on-ones because capt America and Spider man could be severely b**ch slapped by the horsemen...c'mon Cpt America would be dead in 2 secs definitely the 1st in the batlle to die.
I see:
Hulk Vs Apoc
Iron Man vs Archangel
Sunfire vs Spiderman
capt America vs Caliban & Abraham Kieros
an b4 anyone says hulk would destroy Apocalypse this clip was directly off Apoc's bio on Marvel website:
Apocalypse's full extent of powers remain to be revealed, especially to the extent of which powers have since been augmented by alien technology. Apocalypse claims to have control of his body on the molecular level-- allowing him to shape change and elongate with virtually unlimited range, to increase density and allow his body to mimic metals and armors, to teleport, and to be virtually immune to the effects of age. Apocalypse can also increase his strength to levels surpassing that of the Hulk, grow to giant sizes, and gain the power of flight, sometimes through turning his arms into wings or jets. Apocalypse can also transform himself into a variety of human disguises.
He has exhibited energy absorbing and projecting abilities in the past. Apocalypse has been termed an "External," due to his mutant ability of immortality. Briefly, Apocalypse has shown potential to be a powerful psionic.
&
Mastery of alien technology, specifically in regards to genetics and biochemistry
Apoc is stronger and probably smart enough to devise a way to reverse Hulk back to Banner