Speed is equalized so I take it reaction time and such is also equalized.
Still the smoke bomb thing seems suspect. Has no one tried gas weapons on She-Hulk before? Seems like something someone would have thought to use by now.
Oh, speed equalized? That does hurt a lot, since Sakura, while strong, isn't nearly as tough. Though Sakura's still far more agile and was training in dodge-fu, so she's still going to be very hard to tag.
Hulks can often overcome gas by getting angrier, but it does have an effect.
Without speed equalized, it wouldn't be a fair fight as one of the fighters is like peak human level whereas the other is massively hypersonic. And it is true that Sakura is not be as durable or strong, but she still has her jutsus and healing abilities. I think it would be close.
"The Daemon lied with every breath. It could not help itself but to deceive and dismay, to riddle and ruin. The more we conversed, the closer I drew to one singularly ineluctable fact: I would gain no wisdom here."
Forest of Death Sasuke with his Curse Mark had a ~supersonic+ speed feat when he dodged that dude's sonic boom while putting Sakura and Naruto out of harm's way. Current Sakura is actually pretty formidable by Narutoverse standards so obviously she's going to be in the hypersonic+ range.
Not sure. However, Hulk in recent years has been more powerful and harder to affect with stuff than ever before, due to things like increased anger and increased partnership with Banner, so such increases wouldn't transfer to Jen.
Last time I recall Hulk being knocked out with gas was like in some DC crossover where Batman gassed him after luring him to a dock with fish I think. Either way it's his HF that keeps him from passing out, Jen's isn't on par with his but it should be enough to fight off gases or toxins.
Gas has neutralized her multiple times in comics before. Sensational She-Hulk series by John Byrne was loaded with her gassing scenes. And a few years back, a local military dictator rendered her unconscious her using some sort of knockout gas(kolokol-1).
So this gassing tactic will absolutely work on her. Apart from that, I don't see Sakura doing much against Shulkie, given her strength and durability stats along with h2h training.