Mr. X, who came out in Wolv 159 or so can get down when it comes to melee.
Along with learning all kinds of martial arts and killing all his teachers, he also has some kinda telepathy where he knows your next move.
In his first fight with Wolverine, he completely dominates. It isn't until Wolverine goes into berserk that he wins, since he's he becomes unpredictable.
What kind of chance do you give the other guys listed in hand to hand?(melee weapons they usually carry around are ok, no guns)
Fights take place in a cage.
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Well yeah, but no big deal. He knew all about Wolverine and Wolverine knew nothing about him. Besides, he's telepathic! He got his in the end so don't worry about it.