Any brick without a) super speed OR b) space/time manip AND c) sufficient damage output is phucked.
A or B : Gruenwald, despite what some people think of his space race issues, stated that unless you have an extreme level of super speed or are able to manipulate space/time, you are nothing but a statue to the speedster.
C : Even if you are a super speedster or able to manipulate space/time, you need sufficient damage output to put down the Runner. For example, Runner vs Surfer. Surfer has time manip feats yet he can't put down the Runner.
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..even the outer hells are indifferent matters for they bow only to potent and archaic Nodens.