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Honestly I can see him doing well as a shares villain for all of them. Mostly captain America and Spider-Man.
Wolverine has a rouge gallery full of guys of his kind and it would be in interesting to constantly see them at each other.. Slade would make Moonknight relevant and more interesting so I'd like to see them fight with Moonknight at the obvious disadvantage.
Spider-Man has a crap load of super powered foes but seeing him being schooled by a true pro while being able to avoid Slades more nasty tricks and weapons without it seeming like they are holding Slade back would be great. Seeing porkers spider sense only barely save his skin or from a fatal wound is always fun opposed to it saving him from nearly everything without damage.
Punisher is out classed and that in itself would make for a good read, same with gambit to a much lesser extent.
Punisher going back and forth with Slade while on the run would be sweet. His only way to get Slade off his back is to kill who hired hm type of storyline.
When all you do is lose to Nightwing and Arsenal it doesn't garner a whole lot of good will. Unless you are NamorSubby and Golgo, then simply being a DC character is enough to win every fight.
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Unless entering Marvel gets him some sort of upgrade in power, he's not lasting very long as a reoccurring villain for guys like Wolverine if he takes the direct approach and pisses them off.