Strength means nothing if you can't touch your opponent. Neither does speed. Dr. Strange is just as intelligent, if not more. If MM speedrushes at Doc, he'll get consumed by a magical field. MM can't win this fight.
The auto shield is always up, unless the writers forget, or need an excuse for him to be k.o'd.
In a quasar comic, Strange is talking to quasar and Deathurge, from a mile away shoots a poisionous arrow at Strange, and it bounces of his shield.
Only way through it is not having the intent to harm, his house has the same spell of protection.
No possible way to lose without seriously being dumb.