There's a gender ambiguous person in the first episode. That alone should have snowflake Rightists pitching a fit.
Watched the first episode of this last night with my wife. I guess it helps to know the games, because I found it to be pretty terrible in a good way or good in a terrible way. I'm not sure which. I might keep watching just because it looks trippy and for Goggins. Though it seems like he's just doing the same voice he does for Baby Billy from Righteous Gemstones, which is a bit distracting.
Got one more episode of this, it's pretty highly entertaining, but there are some really stupid tropes that I guess were difficult to avoid to just move the plot along...
That being said, I do get a little bit of a James Gunn vibe from it so far, with some of the reveals with Vault 4 and such. That's a compliment.
Just a couple off the top of my head: the idiot organ harvesters who just released the dangerous zombie ghouls without any real argument. The president who specifically told his man to take his gun off of The Ghoul and then told them to take him out and kill him. Of course he's going to fight back if you say that right in front of him. Just shoot him!