James McAvoy has checked into Mandate Pictures' comedic adaptation of the Will Reiser novel "
I'm With Cancer." Nicole Holofcener will direct, and the pic will co-star Seth Rogen, who is also producing.
In the first major project McAvoy has agreed to star in since the Universal comicbook actioner "Wanted" and its upcoming sequel, thesp will play a 25-year-old who learns he has cancer and successfully battles the disease over several years.