Future evolution?
Let's just go with the assumption that evolution is alive and well in the world, shall we? Creatism aside and given a nod.
What direction do you think the human race will go in the upcoming eons, both physically or mentally, or what changes would you like to see no matter how odd.
Think humans will ever spend enough time in space to adapt to the environment? Or how about becoming a more amphibious species? The ocean is the big unconquered unknown second only to space and is a possible direction for humans to go if the land ever gets too over crowded or untenable.