Owen and OB1
I kind of hope they are related, and Owen was jealous of OB1 because of his powers, thus explaining the rift between them. Most people do not know about them being brothers in the EU, so it would come as a surprise to a lot people. I don't think he is the son of Shmi, because "the Force is strong in my family...."-Luke to Leia in ROTJ, and if he were a Skywalker, he would have boat load of Force.
.........
Yes I agree with your last point, JM and the chances of Owen being the brother of Amidala are pretty slim too. I think Luke just calls him Uncle Owen, because it still shows that he is family, without implying that he is his foster father.
Still, I don't think Obi-Wan and Owen should be related. Even if they didn't like each other one bit, you'd think Obi-Wan would have given off some sort of reaction after finding out he was dead.