If a Predator has killed an Alien with its bare hands, I belive it can take Wolvie healing factor or not. Those things bleed acid and tear everything in sight apart. and Still some of the older Predators have killed "Hard Meat" as they call them in a "fist" fight.
and sure a machine gun can drop an Alien, but you dont want to count those things out as easy to kill. in almost any other situation Aliens rip Predators apart in melee combat.
I bet between the wrist blades and spear they can pound Wolverine into putty and then pop off that adamantium head for a spifftastic trophy.
Like I said before concerning "Bat's did it, Tarzan did it" obviosuly Dark hourse has a slew of Predators. DC has ones Bat's they are not going to let him die. he won threw circumsatnces. Batman has beat up Carnage, CARNAGE people, threw circumstances. I dont look at dramatic events are reliable refferences when discussing a vs thread.
Punisher has literally kicked Wolverines ass. and Hulk has done it in a page and a half. but these arent very good vs refferences.
Im not saying all fights that occur are bogus far from it. just some circomstances are pretty screwy.