The film should be all about how they got their powers, and should then led on to their first major battle against Dr. Doom. As for the actors, a good Dr. Doom could be Christan Bale, but that's just my opinion. Reid could be someone like George Cloony or any other celebraty that's 'it' at the moment. The Thing should be computer-animated like Hulk, but Ben Grimm would have to be someone with a big-figure, or someone with padding. I can't think of anyone suitable at the moment. As for Miss Fantasitc, I'd go for Drew Barrymore or Cameron Diaz. As for The Human Torch, I'd go for the guy who played Flash Thompson in Spider-Man.