Another clue for Spider-Man 3.....
Okay, we can speculate all we want about Spider-Man 3, but you all know that I'm all for The Lizard being in Spider-Man 3 and NOT Venom (he should be in 4 - for reasons I have gone over a million times).
Just recently I was taking a look at the details concerning the Spider-Man 2 video game. What strikes me as odd is that The Lizard has been removed from the game (after he was confirmed to be in it for a long time). Now this got me thinking, what would make the developers remove The Lizard from the Spider-Man 2 game? One obvious reason is that The Lizard may be up for the role of the head villain in the NEXT movie, and as a consequence, the game developers couldn't use him as a low-level thug in one game, then in the sequel (which will obviously be out when the 3rd film is) has him as a major villain?
Couple this with the fact there have been massive rumours concerning the Venom-symbiote being in Spidey 3 (not Venom himself, and not dismissing the Lizard rumours either) then it's pointing quite clearly that The Lizard will be in Spidey 3.
Think about it, they know Venom is huge, they know his character takes time to be "born". They know they need to ADVERTISE him. If they merely have Eddie Brock and the venom-symbiote in 3 (not Venom), this would make an awesome cliff-hanger for people to go see 4 (and make 4 one of the first movies to make the "fourth" film better than all the rest).