Supreme vs Superman
Most people will say Superman because they don't know two shits about Supreme, but Supreme has all of Superman's powers, but two fold, and is ruthless from the get-go, no waiting around to check his enemy out.
There was a hostage situation in an airport, and while Young Blood sat around making a strategey, Supreme went in and killed nearly 50 terrorists in 2 or 3 minutes. He used his hands like saws, and cut people's skulls and whole bodies in half, he used his heat vision at close range and blew off a guy's head.
When he fought Van Guard in Van Guard #1, Van's mechanical floating buddy(his name slips my mind at the moment) teleported Supreme to the other side of the sun, and Supreme had to fly through the sun to catch up to the ship, which he instantly dismantled by flying through it a dozen times or so. He then threw the ship away from earth, and it nearly reached light speed. Van teleported and appeared behind Supreme, caught him by surprise and blasted him with a big ass gun, which did hurt Supreme, but he healed almost instantly, and then threw VanGuard from outer space to New York. He chased him closely, beat his ass when he landed, and then put him in jail. Great fight.
My vote goes to Supreme. duh.