Strange kills Supes and GL? I can see him taking out Supes right away Hal Jordan? No way! Hulk takes on the Flash, yes this is a perfect distraction to get Hulk out of the way while the rest of the team does there thing. No matter how mad Hulk gets he's not going to catch him. I say if we throw Plastic Man and Batman in there, JLA. With the current line up, even though i disagree with Beyonder, Defenders still most likley take it.
JLA take the majority. Its five against six. Diana is the best match up against Strange. In the meantime Hal will stalemate Surfer until back up arrives. Or Flash can either help him or Diana. While all this is happening, Clark and John will easily dispose of the Hulk and Namor. The match up wont last long since the Martian will link all of their minds together and operate as one.