of the big "groups" the xmen would proably be the easiest targets.why? is it me or do they have a rabid fascination with playing baseball, or having snowball fights?
all slade has to do is wait til they come back from another adventure. and while thier either healing up or playing out in the front yard just choose the best ones.
jubilee(if she still even exists, i know she's not dead but it seems like she has been excised from continuity for some strange reason)
shadowcat
all the little kids(newbies)
beast
gambit
knowing that after these ones get cut down all the telepaths would be on his trail, just set a trap for all them.
1st. send a giant spike thru wolverine that would pin him to the wall and take him out of the fight. then just kill jean or emma which ever happens to be current or active members and just work his way down from there. the best way would be in some abandoned induustrial complex where he could put his closed quarterd and acrobatic skills to use