- Lizard is faster than Spider-Man. Spider-Man is faster than Sabretooth.
- Lizard is stronger than Spider-Man. Spider-Man is stronger than Sabretooth.
You people do the math...
If we're talking about "classic Sabretooth", this could go either way. Lizard is very dangerous and goes for the kill, just like Sabretooth.
If it's adamantium Sabretooth, than Sabretooth wins.