Brotherhood of Evil Mutants vs. Sinister Six

Only one group of villains can reign supreme this day, but which one?

Sinister Six (third version)
Venom, Mysterio II, Vulture, Electro, Sandman and Kraven (plus Doc Ock just for fun)
vs.
The Brotherhood of Evil Mutants
Mystique, Rogue, Blob, Pyro, Destiny, and Avalanche

So, in an all out war for ultimate victory, who would win? A cake walk for the Brotherhood? Or does the six (seven here) shown the oposistion the meaning of...sinister.

The Brotherhood wins.

They have more fire-power, have more experience fighting
together (and get along together better), and have much
more experience fighting super-powered teams (Z-Men).

The Six cannot compare.

Actually, Rigue herself can take out most of the Sinister Six.